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The following term was not found in PubMed: diazadimethine
Page 1
Second Generation G-Quadruplex Stabilizing Trimethine Cyanines.
Owens EA, Huynh HT, Stroeva EM, Barman A, Ziabrev K, Paul A, Nguyen SV, Laramie M, Hamelberg D, Germann MW, Wilson WD, Henary M. Owens EA, et al. Bioconjug Chem. 2019 Oct 16;30(10):2647-2663. doi: 10.1021/acs.bioconjchem.9b00571. Epub 2019 Sep 26. Bioconjug Chem. 2019. PMID: 31518105 Free PMC article.
We have previously reported pentamethine and symmetric trimethine cyanines designed to effectively bind G-quadruplexes through end stacking interactions. Herein, we are reporting a second generation of drug candidates, the asymmetric trimethine cyanines. These have …
We have previously reported pentamethine and symmetric trimethine cyanines designed to effectively bind G-quadruplexes through end st …
Near-infrared heptamethine cyanines (Cy7): from structure, property to application.
Feng L, Chen W, Ma X, Liu SH, Yin J. Feng L, et al. Org Biomol Chem. 2020 Dec 7;18(46):9385-9397. doi: 10.1039/d0ob01962c. Org Biomol Chem. 2020. PMID: 33191410 Review.
Heptamethine cyanine dyes (Cy7) have attracted much attention in the field of biological application due to their unique structure and attractive near infrared (NIR) photophysical properties. In this review, the influences of different modification sites on the absorption …
Heptamethine cyanine dyes (Cy7) have attracted much attention in the field of biological application due to their unique structure an …
Coumarins to Cyanines: Synthesis of Hemicyanines.
Caldwell DR, Usama SM, Schnermann MJ. Caldwell DR, et al. Org Lett. 2021 Nov 19;23(22):8857-8861. doi: 10.1021/acs.orglett.1c03367. Epub 2021 Nov 9. Org Lett. 2021. PMID: 34752112 Free PMC article.
Synthesis of Heptamethine Cyanines from Furfural Derivatives.
Hao Z, Hu L, Wang X, Liu Y, Mo S. Hao Z, et al. Org Lett. 2023 Feb 24;25(7):1078-1082. doi: 10.1021/acs.orglett.2c04289. Epub 2023 Feb 14. Org Lett. 2023. PMID: 36786486
Despite the widespread theranostic utilization of cyanine dyes (Cy7), their synthetic method is still limited with pyridine or cyclohexanone derivatives as starting materials. ...
Despite the widespread theranostic utilization of cyanine dyes (Cy7), their synthetic method is still limited with pyridine or cycloh …
Optimized Heptamethine Cyanines for Photodynamic Therapy.
Usama SM, Thavornpradit S, Burgess K. Usama SM, et al. ACS Appl Bio Mater. 2018 Oct 15;1(4):1195-1205. doi: 10.1021/acsabm.8b00414. Epub 2018 Sep 17. ACS Appl Bio Mater. 2018. PMID: 34996160
(This is crucial to tumor localization.) The N-substituents of these cyanines were varied to adjust their charges and polarities and to accommodate conjugation to other entities (e.g., biomolecules or fragments to expand their theranostic modalities). ...
(This is crucial to tumor localization.) The N-substituents of these cyanines were varied to adjust their charges and polarities and …
Rejuvenating old fluorophores with new chemistry.
Schnermann MJ, Lavis LD. Schnermann MJ, et al. Curr Opin Chem Biol. 2023 Aug;75:102335. doi: 10.1016/j.cbpa.2023.102335. Epub 2023 Jun 1. Curr Opin Chem Biol. 2023. PMID: 37269674 Review.
Of the extant collection of synthetic fluorescent dyes for biological imaging, two classes reign supreme: rhodamines and cyanines. Here, we provide an overview of recent examples where modern chemistry is used to build these old-but-venerable classes of optically responsiv …
Of the extant collection of synthetic fluorescent dyes for biological imaging, two classes reign supreme: rhodamines and cyanines. He …
Targetable Conformationally Restricted Cyanines Enable Photon-Count-Limited Applications*.
Eiring P, McLaughlin R, Matikonda SS, Han Z, Grabenhorst L, Helmerich DA, Meub M, Beliu G, Luciano M, Bandi V, Zijlstra N, Shi ZD, Tarasov SG, Swenson R, Tinnefeld P, Glembockyte V, Cordes T, Sauer M, Schnermann MJ. Eiring P, et al. Angew Chem Int Ed Engl. 2021 Dec 13;60(51):26685-26693. doi: 10.1002/anie.202109749. Epub 2021 Nov 17. Angew Chem Int Ed Engl. 2021. PMID: 34606673 Free PMC article.
Cyanine dyes are exceptionally useful probes for a range of fluorescence-based applications, but their photon output can be limited by trans-to-cis photoisomerization. ...We demonstrate that a bifunctional sulfonated tertiary amide significantly improves the optical proper …
Cyanine dyes are exceptionally useful probes for a range of fluorescence-based applications, but their photon output can be limited b …
Cyanine Conjugate-Based Biomedical Imaging Probes.
Li Y, Zhou Y, Yue X, Dai Z. Li Y, et al. Adv Healthc Mater. 2020 Nov;9(22):e2001327. doi: 10.1002/adhm.202001327. Epub 2020 Oct 1. Adv Healthc Mater. 2020. PMID: 33000915 Review.
Cyanine is a class of fluorescent dye with meritorious fluorescence properties and has motivated numerous researchers to explore its imaging capabilities by miscellaneous structural modification and functionalization strategies. The covalent conjugation with other function …
Cyanine is a class of fluorescent dye with meritorious fluorescence properties and has motivated numerous researchers to explore its …
Phospha-cyanines in Their Ideal Polymethine State: Synthesis and Structure-Property Relationships.
Chemin A, Knysh I, Ari D, Cordier M, Roisnel T, Guennic BL, Hissler M, Jacquemin D, Bouit PA. Chemin A, et al. J Phys Chem A. 2023 Dec 14;127(49):10457-10463. doi: 10.1021/acs.jpca.3c07039. Epub 2023 Dec 5. J Phys Chem A. 2023. PMID: 38051511
We report the synthesis and full characterization of a family of phosphorus-containing polymethine cyanines (phospha-cyanines). The compounds are easily prepared in two steps, starting from readily available phosphanes. ...All these compounds display the typical …
We report the synthesis and full characterization of a family of phosphorus-containing polymethine cyanines (phospha-cyanines) …
Photophysics and photochemistry of NIR absorbers derived from cyanines: key to new technologies based on chemistry 4.0.
Strehmel B, Schmitz C, Kütahya C, Pang Y, Drewitz A, Mustroph H. Strehmel B, et al. Beilstein J Org Chem. 2020 Mar 18;16:415-444. doi: 10.3762/bjoc.16.40. eCollection 2020. Beilstein J Org Chem. 2020. PMID: 32273905 Free PMC article. Review.
Cyanines derived from heptamethines were mainly discussed regarding their functionalization to broaden the solubility in different surroundings exhibiting either hydrophilic or hydrophobic properties and to tailor made the deltaG (et) photopysical properties with respect t …
Cyanines derived from heptamethines were mainly discussed regarding their functionalization to broaden the solubility in different su …
5,011 results